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Abstract <p>In this article, we described a successful approach to deposition and further local reduction of graphene oxide film for formation of biosensor. We used improved graphene oxide suspension with additional organic solvent by which we obtained better wettability of PET substrate. By local laser reduction of graphene oxide film we made sensor topology with different reduction level. We used thrombin aptamer to form sensitive layer of a biosensor and showed high sensitivity and selectivity of sensor that can be used for new point-of-care devices and personalized medicine in the future.</p>

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A Novel Reduced Graphene Oxide-Based Biosensor for Fast Detection of Thrombin

  • 期刊论文

  • 发表日期：

    2025年2月1日

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  • M. I. Trukhanova,
  • D. D. Levin,
  • K. A. Rayanova,
  • S. I. Babenko,
  • A. S. Bryleva,
  • K. V. Kanaev,
  • R. R. Nigamatullina,
  • A. D. Sudakova,
  • A. V. Shchegolkov,
  • N. V. Myasishcheva,
  • I. A. Komarov

摘要

Abstract

In this article, we described a successful approach to deposition and further local reduction of graphene oxide film for formation of biosensor. We used improved graphene oxide suspension with additional organic solvent by which we obtained better wettability of PET substrate. By local laser reduction of graphene oxide film we made sensor topology with different reduction level. We used thrombin aptamer to form sensitive layer of a biosensor and showed high sensitivity and selectivity of sensor that can be used for new point-of-care devices and personalized medicine in the future.