Abstract <p>Nanophase iron metal (npFe⁰) spherules ranging in size from a few to hundreds of nanometers are a significant component of the regolith of the Moon and other airless bodies affecting the spectrum of electromagnetic wave reflection. Electron microscopy was used to study nanospherules on the surface and within the volume of agglutinate particles from the lunar regolith of Rümker Mons returned to the Earth by the Chang’e-5 mission. The glass hosting the npFe⁰ spherules was characterized by a noticeable oxygen depletion compared with the surrounding unmelted minerals. The oxygen deficiency of the glass contributed to the formation of npFe⁰ and the reduction of elements with low affinity for oxygen, in particular, siderophile elements and sulfur. The spherules were enriched in siderophile elements, including Ni and P, and S relative to the host glass. It can be hypothesized that the increased contents of siderophile elements and sulfur are due to the sorption of their reduced species by iron spherules formed in the glass during active mixing of boiling melt produced by a high-speed impact. The feeding glass zone from which these elements were sorbed was estimated to be up to 3–4 radii of the spherules. Thus, npFe⁰ spherules can act as a kind of repository for siderophile elements and sulfur or as their carrier, when the spherules were ejected into the impact-related vapor cloud.</p>