<p>The latest research on the use of gold nanoparticles obtained by an environmentally friendly method of “green” synthesis is considered. These nanoparticles are obtained with extracts from leaves, bark and seeds of plants of medicinal value, which are combined with gold nanoparticles or other types of nanoparticles. The data referenced in this review are taken from reputable platforms, including Google Scholar, ResearchGate, PubMed, and Scopus. We will show the results of studies that have demonstrated the effects of nanoparticles on tissues. Numerous studies indicate that the toxicity of gold nanoparticles obtained using environmentally friendly methods is minimal. To reduce the impact on the environment, priority should be given to the development of environmentally friendly methods for the synthesis of nanomaterials. In this regard, researchers are looking for “green” methods to close the gaps and reduce possible problems. Biological synthesis processes are economically efficient, non-toxic, relatively uncomplicated, and environmentally friendly. The process of “green” synthesis involves the production of biological compounds from extracts of plants, bacteria and algae. The ability to manipulate the morphological characteristics (such as size, shape, and crystal structure) of gold nanoparticles during their creation plays an important role in a number of fields where nanoparticles are used. Biological molecules derived from plants are suitable for the production of metal nanoparticles. Numerous studies have demonstrated the possibility of using nanoparticles of both gold and other materials to perform therapeutic procedures with minimal impact on healthy tissues. In addition, such nanoparticles have the ability to repair damaged tissues.</p>