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Abstract <p>This article reviews biosynthesis of the valuable fat-soluble compounds with antioxidant activity, in particular vitamin E isomers and carotenoids, in yeast cells. Main genetic engineering approaches to increase microbial production of these substances are described. The main innovative strategies for subcellular separation of synthesis, storage, and recovery of lipophilic compounds are discussed, and examples of cell morphology engineering importance of are shown.</p>

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Yeast Engineering for Antioxidant Production

  • 期刊论文

  • 发表日期：

    2026年2月1日

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  • Yulia S. Panina,
  • Sergey A. Bruskin,
  • Svetlana O. Avdoshina,
  • Liliya G. Maloshenok,
  • Tigran Yuzbashev,
  • Evgeniya Yuzbasheva

摘要

Abstract

This article reviews biosynthesis of the valuable fat-soluble compounds with antioxidant activity, in particular vitamin E isomers and carotenoids, in yeast cells. Main genetic engineering approaches to increase microbial production of these substances are described. The main innovative strategies for subcellular separation of synthesis, storage, and recovery of lipophilic compounds are discussed, and examples of cell morphology engineering importance of are shown.