Abstract <p>A biotechnological method based on the use of aqueous dispersions, or colloidal solutions, of fullerene-containing compounds for the treatment of seed material, which provides growth stimulation and contributes to an increase in plant yield, has been proposed. It was found that aqueous dispersions of fullerene C₆₀ and salts of amino acid derivatives of fullerene C₆₀ possess pronounced antioxidant activity and a wide range of other properties of biological activity. The growth-stimulating effect of aqueous dispersions of fulle-rene C₆₀ and salts of amino acid derivatives of fullerene C₆₀ on plants was shown to be effective in the case of their application for pre-sowing treatment (soaking) of seeds. In field experiments on the example of spring wheat of the “Lada” variety, the increase in plant yield, weight, and number of grains in the ear, which was promoted by pre-sowing treatment of seeds in the presence of fullerene-containing aqueous dispersions, was demonstrated. The proposed biotechnological approach has prospects for effective application in agriculture for seed treatment and increasing yields of important food crops.</p>