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<p>High maternal mortality rates persist as a critical challenge in low-resource settings. Here, in this prospective, observational mixed-methods study, we evaluated a Diagnostic Decision Support System integrated into MomConnect, South Africa’s government-led WhatsApp-based maternal health platform. Between May and June 2023, 968 pregnant women and mothers were enrolled, of whom 86.3% faced multiple barriers to care. Behaviour was assessed via platform surveys and phone interviews at 1-week follow-up. A physician panel rated Diagnostic Decision Support System advice safe in 98.4% (181/184; <i>P</i> &lt; 0.001) of cases. After use, 44.6% (266/596) changed care-seeking intentions, and uncertainty dropped from 17.3% to 6.0%. By follow-up, 43.0% (337/785) had sought care, up from 17.0% initially. Safe behaviours increased by 18.1% (<i>P</i> = 0.001) and appropriate behaviour by 10.5% (<i>P</i> = 0.053). Half of those receiving treatment had not initially planned to seek care. Integrating clinical artificial intelligence into a government health platform was associated with safe advice and improved health-seeking behaviour. ClinicalTrials.gov: NCT06790069; funded by the Rockefeller Foundation.</p>

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An AI-based symptom checker integrated into MomConnect maternal healthcare platform: a prospective, observational mixed-methods study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年6月16日

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  • Marcel Schmude,
  • Stephen Gilbert,
  • Caroline Moor Larsson,
  • Noxolo Gqada,
  • Kris Lemon,
  • Lauren Kotze,
  • Reza Omar,
  • Ebrahim January,
  • Doreen Schlagenhauf,
  • Hila Azadzoy,
  • Tauseef Mehrali,
  • Leo Wolansky,
  • Jane Sebidi,
  • Vedika Kundi,
  • François Bergey,
  • Asmaa Foda,
  • Fabienne Cotte

摘要

High maternal mortality rates persist as a critical challenge in low-resource settings. Here, in this prospective, observational mixed-methods study, we evaluated a Diagnostic Decision Support System integrated into MomConnect, South Africa’s government-led WhatsApp-based maternal health platform. Between May and June 2023, 968 pregnant women and mothers were enrolled, of whom 86.3% faced multiple barriers to care. Behaviour was assessed via platform surveys and phone interviews at 1-week follow-up. A physician panel rated Diagnostic Decision Support System advice safe in 98.4% (181/184; P < 0.001) of cases. After use, 44.6% (266/596) changed care-seeking intentions, and uncertainty dropped from 17.3% to 6.0%. By follow-up, 43.0% (337/785) had sought care, up from 17.0% initially. Safe behaviours increased by 18.1% (P = 0.001) and appropriate behaviour by 10.5% (P = 0.053). Half of those receiving treatment had not initially planned to seek care. Integrating clinical artificial intelligence into a government health platform was associated with safe advice and improved health-seeking behaviour. ClinicalTrials.gov: NCT06790069; funded by the Rockefeller Foundation.