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<p>Organic mixed ionic-electronic conductors are promising materials for next generation bioelectronic devices. While they readily interface with biological systems, the volumetric doping mechanism renders them susceptible to biofouling and operational instability. Thus, there is a materials science challenge requiring strategic focus on rational, molecular-level design of materials to control the complex bio-abiotic interface. Here, biofouling and operational instability are explored, and strategies developed to address these interconnected problems are traced.</p>

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Organic mixed ionic-electronic conductor device platforms for emerging biosensor application

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月19日

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  • Siyu Qin,
  • Zeyuan Sun,
  • Simiao Sun,
  • Jeremy Wang,
  • Charleen Rahman,
  • Thomas E. Gartner III,
  • Xuanhong Cheng,
  • Elsa Reichmanis

摘要

Organic mixed ionic-electronic conductors are promising materials for next generation bioelectronic devices. While they readily interface with biological systems, the volumetric doping mechanism renders them susceptible to biofouling and operational instability. Thus, there is a materials science challenge requiring strategic focus on rational, molecular-level design of materials to control the complex bio-abiotic interface. Here, biofouling and operational instability are explored, and strategies developed to address these interconnected problems are traced.