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<p>Neurodegenerative diseases involve the progressive loss of neurons in the brain and nervous system, leading to functional decline. Early detection is critical for improving outcomes and advancing therapies. Optical biosensors, some of which offer rapid, label-free, and ultra-sensitive detection, have been applied to early diagnosis and drug screening. This review examines the principles and performance of different optical biosensors used for diagnosing neurodegenerative diseases and discusses potential future advancements.</p>

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Optical biosensors for diagnosing neurodegenerative diseases

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年5月2日

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  • Khuong Duy Mac,
  • Judith Su

摘要

Neurodegenerative diseases involve the progressive loss of neurons in the brain and nervous system, leading to functional decline. Early detection is critical for improving outcomes and advancing therapies. Optical biosensors, some of which offer rapid, label-free, and ultra-sensitive detection, have been applied to early diagnosis and drug screening. This review examines the principles and performance of different optical biosensors used for diagnosing neurodegenerative diseases and discusses potential future advancements.