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<p>Optical coherence tomography (OCT) enables high-resolution in vivo assessment of coronary atherosclerosis, identifying vulnerable plaque features linked to progression and adverse cardiovascular events across stable and acute coronary syndromes. OCT-defined high-risk morphology may add information beyond physiology, particularly in diabetes, multivessel disease, and post-ACS residual lesions. However, these findings remain risk markers, not standalone treatment indications. Advances in automation, AI, and hybrid imaging may support clinical translation.</p>

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Optical coherence tomography in the identification and risk stratification of vulnerable coronary plaques

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年8月5日

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  • Panagiotis Theofilis,
  • Paschalis Karakasis,
  • Panayotis K. Vlachakis,
  • Panagiotis Iliakis,
  • Konstantinos Pamporis,
  • Nikolaos Pyrpyris,
  • Nikolaos Ktenopoulos,
  • Evangelos Oikonomou,
  • Kyriakos Dimitriadis,
  • Konstantinos Tsioufis,
  • Dimitris Tousoulis

摘要

Optical coherence tomography (OCT) enables high-resolution in vivo assessment of coronary atherosclerosis, identifying vulnerable plaque features linked to progression and adverse cardiovascular events across stable and acute coronary syndromes. OCT-defined high-risk morphology may add information beyond physiology, particularly in diabetes, multivessel disease, and post-ACS residual lesions. However, these findings remain risk markers, not standalone treatment indications. Advances in automation, AI, and hybrid imaging may support clinical translation.