<p>Breast arterial calcification (BAC), frequently visible on screening mammography, is a potent biomarker for cardiovascular disease risk in women. Unlike atherosclerosis, BAC represents medial arterial calcification characterized by arterial stiffness rather than narrowing. BAC has been linked to myocardial infarction, stroke, and heart failure and may offer a scalable risk stratification tool through AI-driven quantification. Standardizing BAC measurement and reporting is essential to improving long-term clinical outcomes for women.</p>

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Review of breast arterial calcifications for cardiovascular disease risk prediction

  • Brandy Ndirangu,
  • Judy Gichoya,
  • Theo Dapamede,
  • Frank Li,
  • Mohammadreza Chavoshi,
  • Beatrice Brown-Mulry,
  • Rohan Isaac,
  • Aawez Mansuri,
  • Chiratidzo Sanyika,
  • Puja Mehta,
  • W. Charles O’Neill,
  • Hari Trivedi

摘要

Breast arterial calcification (BAC), frequently visible on screening mammography, is a potent biomarker for cardiovascular disease risk in women. Unlike atherosclerosis, BAC represents medial arterial calcification characterized by arterial stiffness rather than narrowing. BAC has been linked to myocardial infarction, stroke, and heart failure and may offer a scalable risk stratification tool through AI-driven quantification. Standardizing BAC measurement and reporting is essential to improving long-term clinical outcomes for women.