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<p>Drug-coated balloons (DCBs) provide a “leave-nothing-behind” revascularization strategy, delivering antiproliferative therapy without permanent implants. This review presents evidence on DCB performance across coronary indications. In in-stent restenosis and de novo disease, DCBs are associated with higher rates of repeat revascularization compared to drug-eluting stents (DES). In small vessel disease, DCBs achieve comparable or sometimes superior outcomes. In complex lesions or high-risk patients, dedicated studies demonstrate feasibility and signals of non-inferiority.</p>

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Drug-coated balloon angioplasty in coronary artery disease: state of the art review

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年5月16日

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  • Panagiotis Theofilis,
  • Aggelos Papanikolaou,
  • Kyriakos Dimitriadis,
  • Paschalis Karakasis,
  • Panagiotis Iliakis,
  • Konstantinos Aznaouridis,
  • Konstantinos Tsioufis,
  • Dimitris Tousoulis

摘要

Drug-coated balloons (DCBs) provide a “leave-nothing-behind” revascularization strategy, delivering antiproliferative therapy without permanent implants. This review presents evidence on DCB performance across coronary indications. In in-stent restenosis and de novo disease, DCBs are associated with higher rates of repeat revascularization compared to drug-eluting stents (DES). In small vessel disease, DCBs achieve comparable or sometimes superior outcomes. In complex lesions or high-risk patients, dedicated studies demonstrate feasibility and signals of non-inferiority.