Scholarlink

<p>Apolipoproteins are structural components of lipoproteins involved in assembly, enzyme regulation, structural integrity, and receptor binding. Apoprotein(a) forms lipoprotein(a), apolipoprotein A-I drives reverse cholesterol transport, apolipoprotein B reflects atherogenic particle number, and apolipoprotein C-III regulates triglycerides. This review highlights the clinical significance of these apolipoproteins in coronary plaque characteristics detected by imaging modality. Additionally, we summarize the current clinical status of therapeutic agents targeting these apolipoproteins and its future potential.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

A narrative review of impacts of apolipoproteins on atherosclerotic coronary plaques

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月2日

查看全文
  • Tatsuya Fukase,
  • Tomotaka Dohi

摘要

Apolipoproteins are structural components of lipoproteins involved in assembly, enzyme regulation, structural integrity, and receptor binding. Apoprotein(a) forms lipoprotein(a), apolipoprotein A-I drives reverse cholesterol transport, apolipoprotein B reflects atherogenic particle number, and apolipoprotein C-III regulates triglycerides. This review highlights the clinical significance of these apolipoproteins in coronary plaque characteristics detected by imaging modality. Additionally, we summarize the current clinical status of therapeutic agents targeting these apolipoproteins and its future potential.