Scholarlink

<p>Ischemic heart disease (IHD) is a leading cause of mortality worldwide, primarily driven by coronary artery stenosis. Current therapies predominantly slow disease progression, with limited capacity to restore functional myocardium. Worsening metabolic disorders significantly drives heart failure. Emerging evidence suggests that stem cell therapy may improve cardiac metabolism. This review examines metabolic dysregulation in IHD and explores how stem cells and extracellular vesicles could modulate these pathways to support tissue repair.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Metabolic regulation for the treatment of ischemic heart disease with stem cells and extracellular vesicles

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年10月10日

查看全文
  • Shouting Liu,
  • Lei Jin,
  • Jiaxin Zhang,
  • Xinyi Zhang,
  • Yikai Shi,
  • Zheng Tu,
  • Junjun Xu

摘要

Ischemic heart disease (IHD) is a leading cause of mortality worldwide, primarily driven by coronary artery stenosis. Current therapies predominantly slow disease progression, with limited capacity to restore functional myocardium. Worsening metabolic disorders significantly drives heart failure. Emerging evidence suggests that stem cell therapy may improve cardiac metabolism. This review examines metabolic dysregulation in IHD and explores how stem cells and extracellular vesicles could modulate these pathways to support tissue repair.