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<p>Invasive fungal diseases (IFDs) present a growing clinical challenge, underscoring the urgent need for improved diagnostics, therapeutics and mechanistic understanding. This review highlights the key role of innovative imaging techniques across all scales - ranging from whole-body-level diagnostics and therapy monitoring to host-pathogen interactions at cellular resolution in both clinical and preclinical settings. These imaging modalities facilitate translation of preclinical innovations into clinical applications, accelerating research and advancing IFD management.</p><p></p>

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Fungal infections in focus: accelerating non-invasive imaging from preclinical insights to clinical breakthroughs

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月16日

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  • Lauren Michiels,
  • Mahrukh Shameem,
  • Eliane Vanhoffelen,
  • Agustin Reséndiz-Sharpe,
  • Simon A. Johnston,
  • Nicolas Beziere,
  • Greetje Vande Velde

摘要

Invasive fungal diseases (IFDs) present a growing clinical challenge, underscoring the urgent need for improved diagnostics, therapeutics and mechanistic understanding. This review highlights the key role of innovative imaging techniques across all scales - ranging from whole-body-level diagnostics and therapy monitoring to host-pathogen interactions at cellular resolution in both clinical and preclinical settings. These imaging modalities facilitate translation of preclinical innovations into clinical applications, accelerating research and advancing IFD management.