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<p>Endometriosis and fibroids are prevalent uterine conditions. Mechanisms for both conditions—immune dysfunction, inflammation, and sex hormone dysfunction—are plausibly influenced by diet. Here, we review the epidemiology and pathophysiology, and synthesize evidence on dietary patterns, endometriosis and uterine fibroid prevalence, risk, and symptomology. The evidence (12 studies) suggests that low-quality diets (ultra-processed) are associated with higher rates of both conditions, and high-quality diets are associated with lower symptom burden.</p>

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State of the science and research opportunities on dietary patterns in endometriosis and uterine fibroids

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年3月3日

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  • Trina M. Fresco,
  • Lisa M. Tussing-Humphreys,
  • Sage J. Kim,
  • Mary Dawn Koenig,
  • Saria Lofton,
  • Pamela Pearson,
  • Vanessa M. Oddo

摘要

Endometriosis and fibroids are prevalent uterine conditions. Mechanisms for both conditions—immune dysfunction, inflammation, and sex hormone dysfunction—are plausibly influenced by diet. Here, we review the epidemiology and pathophysiology, and synthesize evidence on dietary patterns, endometriosis and uterine fibroid prevalence, risk, and symptomology. The evidence (12 studies) suggests that low-quality diets (ultra-processed) are associated with higher rates of both conditions, and high-quality diets are associated with lower symptom burden.