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<p>Endometriosis is a chronic gynecological disease negatively impacting the health of women and is characterized by the presence of ectopic endometrial-like lesions. The immune system is implicated in endometriosis pathogenesis by promoting endometrial cell survival and creating a microenvironment for lesion development and growth. Neutrophils are phagocytic cells that degranulate, form neutrophil extracellular traps, and recruit immune cells to lesions. Herein we discuss the roles of neutrophils in endometriosis pathogenesis.</p>

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An emerging role for neutrophils in the pathogenesis of endometriosis

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年2月7日

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  • Taylor R. Wilson,
  • Susan Kasper,
  • Katherine A. Burns

摘要

Endometriosis is a chronic gynecological disease negatively impacting the health of women and is characterized by the presence of ectopic endometrial-like lesions. The immune system is implicated in endometriosis pathogenesis by promoting endometrial cell survival and creating a microenvironment for lesion development and growth. Neutrophils are phagocytic cells that degranulate, form neutrophil extracellular traps, and recruit immune cells to lesions. Herein we discuss the roles of neutrophils in endometriosis pathogenesis.