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<p>Plants do not produce Vitamin B<sub>12</sub>, creating a nutrient insufficiency risk for those who do not consume animal-derived foods&#xa0;without supplementation. Furthermore, various diseases cause Vitamin B<sub>12</sub> deficiency. Here, we establish an approach for B<sub>12</sub> dietary supplementation that harnesses a horticultural technology to deliver the recommended daily allowance (RDA) of B<sub>12</sub> within a single portion of a salad crop (pea shoots). We demonstrate the effectiveness of the approach in a commercial and scalable growing environment, conducted an economic evaluation, find that it has versatility for growers, does not alter the product shelf-life, and that the B<sub>12</sub> persists during cold-chain storage. Furthermore, the RDA of B<sub>12</sub> is bioaccessible from this crop during simulated human digestion. Taken together, this provides a commercially-viable approach for dietary supplementation of B<sub>12</sub> intake, and a roadmap for the development and evaluation of fortification strategies.</p>

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Addressing Vitamin B12 deficiency through aeroponic fortification of a salad crop (Pisum sativum)

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年3月6日

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  • Bethany M. Eldridge,
  • Sree Gowrinadh Javvadi,
  • Natalia Perez-Moral,
  • Jessie Sweetman,
  • Luíza Lane de Barros Dantas,
  • Shikha Saha,
  • Deirdre A. Lynch,
  • Thomas Hunt,
  • Sophie E. Clough,
  • Jemal Toussaint,
  • Andy Worrall,
  • Lillian R. Manzoni,
  • Nigel Robinson,
  • Keara A. Franklin,
  • Cathrina H. Edwards,
  • Jonathan Clarke,
  • Jack Farmer,
  • Martin Warren,
  • Antony N. Dodd

摘要

Plants do not produce Vitamin B12, creating a nutrient insufficiency risk for those who do not consume animal-derived foods without supplementation. Furthermore, various diseases cause Vitamin B12 deficiency. Here, we establish an approach for B12 dietary supplementation that harnesses a horticultural technology to deliver the recommended daily allowance (RDA) of B12 within a single portion of a salad crop (pea shoots). We demonstrate the effectiveness of the approach in a commercial and scalable growing environment, conducted an economic evaluation, find that it has versatility for growers, does not alter the product shelf-life, and that the B12 persists during cold-chain storage. Furthermore, the RDA of B12 is bioaccessible from this crop during simulated human digestion. Taken together, this provides a commercially-viable approach for dietary supplementation of B12 intake, and a roadmap for the development and evaluation of fortification strategies.