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<p>South Asians experience disproportionately elevated cardiometabolic disease risk yet remain underrepresented in genomic research. The OurHealth Study builds a digital biobank of US South Asian adults, integrating remote surveys, mailed biospecimens for sequencing, and electronic health record sharing to identify genetic and non-genetic drivers of cardiometabolic disease. By pairing remote participation with culturally tailored outreach, OurHealth enhances accessibility, supports granular phenotyping, and addresses logistical barriers to genomic research inclusion.</p>

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The OurHealth Study: A digital genomic cohort for cardiometabolic risk mechanisms in US South Asians

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年1月16日

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  • Shriienidhie Ganesh,
  • Romit Bhattacharya,
  • Aarushi Bhatnagar,
  • Rishi Madnani,
  • Christine Russo,
  • Sara Haidermota,
  • Bhaavana Oruganty,
  • Harshil Bhavsar,
  • Priyansh Shah,
  • Sarah Pitafi,
  • Nishant Uppal,
  • Namrata Sengupta,
  • Kenneth Rice,
  • Matthew P. Conomos,
  • Ravi Dave,
  • Abha Khandelwal,
  • Aniruddh P. Patel,
  • Kaavya Paruchuri,
  • Yamini Levitsky,
  • Sanchita Singal Parulkar,
  • Rohan Khera,
  • Martha Gulati,
  • Amit V. Khera,
  • Whitney E. Hornsby,
  • Latha Palaniappan,
  • Pradeep Natarajan

摘要

South Asians experience disproportionately elevated cardiometabolic disease risk yet remain underrepresented in genomic research. The OurHealth Study builds a digital biobank of US South Asian adults, integrating remote surveys, mailed biospecimens for sequencing, and electronic health record sharing to identify genetic and non-genetic drivers of cardiometabolic disease. By pairing remote participation with culturally tailored outreach, OurHealth enhances accessibility, supports granular phenotyping, and addresses logistical barriers to genomic research inclusion.