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<p>To investigate the feasibility of two-dimensional shear wave elastography (2D-SWE) for assessing the elasticity of fetal lungs and livers at different gestational ages (GAs). (1) Lung and liver elasticity of normal fetuses was measured using 2D-SWE in 30 cases at different GAs, and changes in the lung and liver elasticity of fetuses at different GAs were analyzed. (2) The lung and liver elasticity of 20 fetuses with congenital heart disease (CHD) were measured and compared with those of normal fetuses to analyze the differences. (1) Fetal lung and liver elasticity significantly increased between 21 and 29 GA. (2) Fetal liver elasticity was consistently greater than lung elasticity. (3) The fetal lung-to-liver ratio (LLE ratio) was constant and equal to 0.87 before 29&#xa0;weeks of gestation. (4) The lung and liver elasticity of fetuses with CHD within 21 to 25&#xa0;weeks of gestation was significantly lower than that of the normal group (<i>P</i> &lt; 0.05). 2D-SWE can be used to quantitatively assess fetal lung and liver elasticity, which can reflect changes in fetal lung and liver elasticity with different GAs.</p>

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A pilot study on the assessment of fetal lung and liver elasticity by two-dimensional shear wave elastography in congenital heart disease

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月28日

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  • Danyi Liu,
  • Liyue Hong,
  • Hongwei Lai,
  • Qiuxia Jiang,
  • Shaozheng He,
  • Guorong Lyu

摘要

To investigate the feasibility of two-dimensional shear wave elastography (2D-SWE) for assessing the elasticity of fetal lungs and livers at different gestational ages (GAs). (1) Lung and liver elasticity of normal fetuses was measured using 2D-SWE in 30 cases at different GAs, and changes in the lung and liver elasticity of fetuses at different GAs were analyzed. (2) The lung and liver elasticity of 20 fetuses with congenital heart disease (CHD) were measured and compared with those of normal fetuses to analyze the differences. (1) Fetal lung and liver elasticity significantly increased between 21 and 29 GA. (2) Fetal liver elasticity was consistently greater than lung elasticity. (3) The fetal lung-to-liver ratio (LLE ratio) was constant and equal to 0.87 before 29 weeks of gestation. (4) The lung and liver elasticity of fetuses with CHD within 21 to 25 weeks of gestation was significantly lower than that of the normal group (P < 0.05). 2D-SWE can be used to quantitatively assess fetal lung and liver elasticity, which can reflect changes in fetal lung and liver elasticity with different GAs.