Scholarlink

<p>Post-infarction ventricular septal rupture (PIVSR) complicated by cardiogenic shock carries an extremely high mortality rate. While surgical or interventional repair is the definitive treatment, optimal timing remains challenging due to hemodynamic instability. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) may stabilize patients and serve as a bridge to delayed repair, but its role requires further investigation. This retrospective case series analyzed all PIVSR patients with cardiogenic shock who received VA-ECMO at two Chinese cardiovascular centers between February 2022 and December 2024. During the study period, 28 PIVSR patients were admitted, including 19 (67.9%) with cardiogenic shock. Seven patients received VA-ECMO (median SAVE score: − 6). Following ECMO support, 6 patients (85.7%) achieved hemodynamic stability and underwent delayed surgical repair (median delay from infarction to surgery: 25 days; range 7–48 days). In-hospital survival was 100%, and 90-day survival was 83.3%. Common complications included gastrointestinal bleeding (4/6, 66.7%) and pulmonary infection (5/6, 83.3%), which were managed effectively. In carefully selected PIVSR patients with cardiogenic shock, early VA-ECMO support provides effective circulatory stabilization and serves as a successful bridge to delayed surgical repair, enabling favorable survival outcomes.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Veno-arterial ECMO as a bridge to delayed repair in post-infarction ventricular septal rupture with cardiogenic shock

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年7月24日

查看全文
  • Tianlong Li,
  • Linhu Hu,
  • Jiarui Zhao,
  • Lu Liu,
  • Juan Chen,
  • Jingchao Luo,
  • Jiajia Li,
  • Jiakun Tian

摘要

Post-infarction ventricular septal rupture (PIVSR) complicated by cardiogenic shock carries an extremely high mortality rate. While surgical or interventional repair is the definitive treatment, optimal timing remains challenging due to hemodynamic instability. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) may stabilize patients and serve as a bridge to delayed repair, but its role requires further investigation. This retrospective case series analyzed all PIVSR patients with cardiogenic shock who received VA-ECMO at two Chinese cardiovascular centers between February 2022 and December 2024. During the study period, 28 PIVSR patients were admitted, including 19 (67.9%) with cardiogenic shock. Seven patients received VA-ECMO (median SAVE score: − 6). Following ECMO support, 6 patients (85.7%) achieved hemodynamic stability and underwent delayed surgical repair (median delay from infarction to surgery: 25 days; range 7–48 days). In-hospital survival was 100%, and 90-day survival was 83.3%. Common complications included gastrointestinal bleeding (4/6, 66.7%) and pulmonary infection (5/6, 83.3%), which were managed effectively. In carefully selected PIVSR patients with cardiogenic shock, early VA-ECMO support provides effective circulatory stabilization and serves as a successful bridge to delayed surgical repair, enabling favorable survival outcomes.