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<p>Green carbon quantum dots (CQDs) with minimal environmental damage can be used as a fluorescent probe. Owing to their non-toxicity and high solubility in water, they can play a significant role in environmental monitoring and water safety. Here, a straightforward hydrothermal process using a home microwave was used to create CQDs using chicory leaves known as Cichorium Intybus. The probe was used for the determination of cefdinir (CFD) in various samples such as biological and pharmaceuticals to verify the practicality of the proposed method. The CQDs showed a fluorescence with the wavelength varying from 375 to 500 nm and the maximum emission wavelength being at 419 nm. The linear range was 10&#xa0;nmol L<sup>−1</sup>&#xa0;to 700&#xa0;nmol L<sup>−1</sup> with a detection limit of <Emphasis Type="BoldItalic">CFD</Emphasis> of 3.00&#xa0;nmol L<sup>−1</sup>. Based on the ideas of click chemistry principles, the “Click Analytical Chemistry Index” (CACI) is a tool for evaluating and contrasting the usefulness and application of analytical techniques. This work broadens the use of CQDs in pharmaceutical analysis, spiked plasma and synthetic urine samples. CACI tool guaranteed that upcoming analytical techniques using the CQDs fluorescence probe satisfy the changing needs of both industrial applications and scientific research.</p>

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Microwave-assisted eco-friendly synthesis of carbon quantum dots derived Cichorium intybus for fluorometric detection of cefdinir

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月22日

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  • El-Sayed Khafagy,
  • Amr Selim Abu Lila,
  • Ashraf M. Ashmawy,
  • Ahmed Al Saqr,
  • Mohammed F. Aldawsari,
  • Ahmed M. Abdel-Raoof

摘要

Green carbon quantum dots (CQDs) with minimal environmental damage can be used as a fluorescent probe. Owing to their non-toxicity and high solubility in water, they can play a significant role in environmental monitoring and water safety. Here, a straightforward hydrothermal process using a home microwave was used to create CQDs using chicory leaves known as Cichorium Intybus. The probe was used for the determination of cefdinir (CFD) in various samples such as biological and pharmaceuticals to verify the practicality of the proposed method. The CQDs showed a fluorescence with the wavelength varying from 375 to 500 nm and the maximum emission wavelength being at 419 nm. The linear range was 10 nmol L−1 to 700 nmol L−1 with a detection limit of CFD of 3.00 nmol L−1. Based on the ideas of click chemistry principles, the “Click Analytical Chemistry Index” (CACI) is a tool for evaluating and contrasting the usefulness and application of analytical techniques. This work broadens the use of CQDs in pharmaceutical analysis, spiked plasma and synthetic urine samples. CACI tool guaranteed that upcoming analytical techniques using the CQDs fluorescence probe satisfy the changing needs of both industrial applications and scientific research.