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<p>We report an optimized implementation of spectral-domain quantum optical coherence tomography (SD-QOCT) capable of acquiring axial scans (A-scans) of multilayer samples in the absence of mechanical scanning, at an unprecedented speed. Implementing a novel strategy, we demonstrate a proof-of-concept system that integrates a diffraction grating, a high-resolution intensified CCD camera and a high-flux photon-pair source operating in the VIS–NIR region (<InlineEquation ID="IEq1"><EquationSource Format="TEX">\(\approx\)</EquationSource></InlineEquation>800 nm). This configuration enables the acquisition of an entire marginal SD-QOCT interferogram in a single camera exposure, yielding a transverse A-scan with a record acquisition time of 100 ms for a mirror sample, which extends to 10 s for a glass coverslip, and a penetration depth of <InlineEquation ID="IEq2"><EquationSource Format="TEX">\(\approx\)</EquationSource></InlineEquation>4 mm. The measured interferometric response shows excellent agreement with the theoretical model. These results represent a decisive step toward the practical deployment of SD-QOCT as a competitive imaging modality for biomedical applications.</p>

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Sub-second a-scan acquisition using marginal spectral-domain quantum optical coherence tomography

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月7日

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  • P. D. Yepiz-Graciano,
  • D. Salamanca-Roldán,
  • H. Cruz-Ramírez,
  • A. B. U’Ren,
  • R. Ramírez-Alarcón

摘要

We report an optimized implementation of spectral-domain quantum optical coherence tomography (SD-QOCT) capable of acquiring axial scans (A-scans) of multilayer samples in the absence of mechanical scanning, at an unprecedented speed. Implementing a novel strategy, we demonstrate a proof-of-concept system that integrates a diffraction grating, a high-resolution intensified CCD camera and a high-flux photon-pair source operating in the VIS–NIR region (\(\approx\)800 nm). This configuration enables the acquisition of an entire marginal SD-QOCT interferogram in a single camera exposure, yielding a transverse A-scan with a record acquisition time of 100 ms for a mirror sample, which extends to 10 s for a glass coverslip, and a penetration depth of \(\approx\)4 mm. The measured interferometric response shows excellent agreement with the theoretical model. These results represent a decisive step toward the practical deployment of SD-QOCT as a competitive imaging modality for biomedical applications.