Scholarlink

<p>Patients with post-COVID condition (PCC) frequently report reduced quality of life (QoL). This study assessed QoL and health-related QoL (HRQoL) with trajectories within a prospective PCC cohort. The study included adult patients at a PCC clinic. Outcomes were collected at 0, 3, 6, and 12 months. The primary outcome was QoL by Visual Analogue Scale (VAS 0–10). Secondary outcomes included QoL by EUROHIS-QOL-8 and HRQoL by 15D, and patients’ symptom perceptions by Somatic Symptom Disorder - B Criteria Scale (SSD-12). Linear mixed models analyzed temporal changes, and trajectory analysis modeled recovery patterns. At baseline, 442 patients participated, with 305 (69.0%) providing follow-up data. Most patients (92.7%) were non-hospitalized. Trajectory analysis of EUROHIS-QOL-8 identified two recovering trajectories (73.8%) and a stable group (26.2%). Stable trajectories were associated with more comorbidities and higher levels of worry-inducing symptom perceptions (mean SSD-12 score 26 out of 48), whereas marked recovery was linked to being employed and having lower SSD-12 (10–13). Mean QoL improved over 12 months from 5.2 to 6.5 on the 0–10 VAS scale and from 3.1 to 3.5 on the EUROHIS-QOL-8 scale of 1–5. HRQoL by 15D increased from 0.76 to 0.80 (scale 0–1). In conclusion, patients with comorbidities and distressing illness beliefs are the most vulnerable group in rehabilitation and require specific attention.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

The course and trajectories of quality of life among post-COVID-19 patients in the HUS long covid cohort study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月24日

查看全文
  • Hélène Rotkirch Virrantaus,
  • Maria Sirén,
  • Mikko Varonen,
  • Jari Arokoski,
  • Mari Kanerva,
  • Kirsi Kvarnström,
  • Antti Malmivaara,
  • Markku Sainio †,
  • Sanna Juutistenaho,
  • Aleksandra Sulg,
  • Velina Vangelova-Korpinen,
  • Aki Vuokko,
  • Mikko S. Venäläinen,
  • Helena Liira

摘要

Patients with post-COVID condition (PCC) frequently report reduced quality of life (QoL). This study assessed QoL and health-related QoL (HRQoL) with trajectories within a prospective PCC cohort. The study included adult patients at a PCC clinic. Outcomes were collected at 0, 3, 6, and 12 months. The primary outcome was QoL by Visual Analogue Scale (VAS 0–10). Secondary outcomes included QoL by EUROHIS-QOL-8 and HRQoL by 15D, and patients’ symptom perceptions by Somatic Symptom Disorder - B Criteria Scale (SSD-12). Linear mixed models analyzed temporal changes, and trajectory analysis modeled recovery patterns. At baseline, 442 patients participated, with 305 (69.0%) providing follow-up data. Most patients (92.7%) were non-hospitalized. Trajectory analysis of EUROHIS-QOL-8 identified two recovering trajectories (73.8%) and a stable group (26.2%). Stable trajectories were associated with more comorbidities and higher levels of worry-inducing symptom perceptions (mean SSD-12 score 26 out of 48), whereas marked recovery was linked to being employed and having lower SSD-12 (10–13). Mean QoL improved over 12 months from 5.2 to 6.5 on the 0–10 VAS scale and from 3.1 to 3.5 on the EUROHIS-QOL-8 scale of 1–5. HRQoL by 15D increased from 0.76 to 0.80 (scale 0–1). In conclusion, patients with comorbidities and distressing illness beliefs are the most vulnerable group in rehabilitation and require specific attention.