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<p>The contemporary addiction landscape is characterized by a high prevalence of polysubstance use. Here, we investigated the associations of delay discounting (DD) and other recovery outcomes with proportion of remission (PrR; i.e., the proportion of substances an individual is in remission from relative to lifetime SUD history), a continuous construct that may better capture progress towards recovery in polysubstance use. Individuals (<i>n</i> = 2,097) with poly-substance use disorder (polySUD) were recruited from the International Quit &amp; Recovery Registry (IQRR). Individuals completed a $1000 adjusting amount DD task, and questions about current and past substance use. We report that DD was significantly associated with PrR in individuals with polySUD. In addition, recovery related variables, i.e., maximum time in recovery, and maximum quit time also were significantly associated with PrR. Further, we found that the relationship between maximum time in recovery and PrR was serially mediated by DD and maximum quit time across substances. Together, interventions that focus on harm reduction and/or those that modulate DD may lead to improved clinical outcomes (including quit time and PrR) in individuals with a history of polysubstance use.</p>

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Polysubstance use: delay discounting in relationship to remission

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月6日

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  • Fatima Quddos,
  • Devin C. Tomlinson,
  • Rafaela M. Fontes,
  • Warren K. Bickel,
  • Allison N. Tegge

摘要

The contemporary addiction landscape is characterized by a high prevalence of polysubstance use. Here, we investigated the associations of delay discounting (DD) and other recovery outcomes with proportion of remission (PrR; i.e., the proportion of substances an individual is in remission from relative to lifetime SUD history), a continuous construct that may better capture progress towards recovery in polysubstance use. Individuals (n = 2,097) with poly-substance use disorder (polySUD) were recruited from the International Quit & Recovery Registry (IQRR). Individuals completed a $1000 adjusting amount DD task, and questions about current and past substance use. We report that DD was significantly associated with PrR in individuals with polySUD. In addition, recovery related variables, i.e., maximum time in recovery, and maximum quit time also were significantly associated with PrR. Further, we found that the relationship between maximum time in recovery and PrR was serially mediated by DD and maximum quit time across substances. Together, interventions that focus on harm reduction and/or those that modulate DD may lead to improved clinical outcomes (including quit time and PrR) in individuals with a history of polysubstance use.