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<p>Recent advances in 27-gauge vitrectomy technology have led to the development of 20,000 cuts-per-minute (CPM; 20&#xa0;K) systems aimed at enhancing surgical efficiency. While experimental data suggest that higher cutting rates may improve vitreous removal, clinical evidence directly comparing 20&#xa0;K and 10&#xa0;K (10,000 CPM) systems remains limited. This study compared the efficacy and safety of 27-gauge vitrectomy systems operating at 20&#xa0;K versus 10&#xa0;K in epiretinal membrane (ERM) surgery. In a single-center, single-masked, prospective randomized clinical trial, 66 eyes with idiopathic ERM were assigned to either the 20&#xa0;K group (<i>n</i> = 33) or the 10&#xa0;K group (<i>n</i> = 33). Patients with secondary ERM, prior vitreoretinal surgery, or coexisting retinal disease were excluded. Surgeries were performed by five retinal surgeons, with randomization stratified by surgeon. The 20&#xa0;K group underwent surgery using the HYPERVIT<sup>®</sup> cutter (Alcon Inc., Fort Worth, TX, USA), while the 10&#xa0;K group was treated with the Advanced ULTRAVIT<sup>®</sup> cutter (Alcon Inc.). The 20&#xa0;K group showed a notable reduction in vitrectomy time compared to the 10&#xa0;K group. There were no significant differences in observed adverse events, as well as visual and anatomical outcomes. These findings suggest that the 20&#xa0;K system improves surgical efficiency.</p>

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Comparison of 27-Gauge 20,000 vs. 10,000 cuts per minute vitrectomy systems in epiretinal membrane surgery: a randomized clinical trial

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年5月14日

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  • Yong Je Choi,
  • Se Joon Woo,
  • Kwangsic Joo,
  • Min Seok Kim,
  • Hyeong Min Kim,
  • Kyu Hyung Park

摘要

Recent advances in 27-gauge vitrectomy technology have led to the development of 20,000 cuts-per-minute (CPM; 20 K) systems aimed at enhancing surgical efficiency. While experimental data suggest that higher cutting rates may improve vitreous removal, clinical evidence directly comparing 20 K and 10 K (10,000 CPM) systems remains limited. This study compared the efficacy and safety of 27-gauge vitrectomy systems operating at 20 K versus 10 K in epiretinal membrane (ERM) surgery. In a single-center, single-masked, prospective randomized clinical trial, 66 eyes with idiopathic ERM were assigned to either the 20 K group (n = 33) or the 10 K group (n = 33). Patients with secondary ERM, prior vitreoretinal surgery, or coexisting retinal disease were excluded. Surgeries were performed by five retinal surgeons, with randomization stratified by surgeon. The 20 K group underwent surgery using the HYPERVIT® cutter (Alcon Inc., Fort Worth, TX, USA), while the 10 K group was treated with the Advanced ULTRAVIT® cutter (Alcon Inc.). The 20 K group showed a notable reduction in vitrectomy time compared to the 10 K group. There were no significant differences in observed adverse events, as well as visual and anatomical outcomes. These findings suggest that the 20 K system improves surgical efficiency.