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<p>This retrospective study evaluated the relationship between pulp volume (PV) and pulp/tooth volume ratio (PTVR) derived from CBCT images of permanent mandibular central incisors for age estimation in 106 children and adolescents aged 8–17.1 years (mean age 12.14 ± 2.24). Three-dimensional segmentation was performed using 3D Slicer to calculate volumetric parameters, followed by sex-stratified correlation and linear regression analyses. In the total sample, weak but significant negative correlations were observed between age and both PV and PTVR (<i>r</i> = − 0.219 to − 0.234; <i>p</i> &lt; 0.05). Sex-stratified analysis revealed significant correlations in females for right PV (<i>r</i> = − 0.327), right PTVR (<i>r</i> = − 0.357), and left PTVR (<i>r</i> = − 0.310), whereas no significant correlations were found in males (<i>p</i> &gt; 0.05). In females, simple regression models based on right PV ®² = 8.8%) and right/left PTVR ®² = 11.0% and 7.7%) were significant. In the total sample, simple models were significant but weak ®² = 3.9–4.4%). No sex or side differences were detected (<i>p</i> &gt; 0.05). Although CBCT-based volumetric parameters reflect age-related pulpal changes, they demonstrate limited standalone predictive value in this pediatric cohort. Nevertheless, their observed right–left symmetry and sex independence suggest they may serve as supportive biometric indicators within comprehensive forensic age estimation protocols requiring cautious interpretation.</p>

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CBCT-based volumetric analysis of mandibular central incisors for age estimation in children and adolescents: a pilot study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年5月4日

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  • Yelda Polat Yavuz,
  • Gizem Karagöz Doğan,
  • Barış Can Güzel,
  • İzzet Yavuz

摘要

This retrospective study evaluated the relationship between pulp volume (PV) and pulp/tooth volume ratio (PTVR) derived from CBCT images of permanent mandibular central incisors for age estimation in 106 children and adolescents aged 8–17.1 years (mean age 12.14 ± 2.24). Three-dimensional segmentation was performed using 3D Slicer to calculate volumetric parameters, followed by sex-stratified correlation and linear regression analyses. In the total sample, weak but significant negative correlations were observed between age and both PV and PTVR (r = − 0.219 to − 0.234; p < 0.05). Sex-stratified analysis revealed significant correlations in females for right PV (r = − 0.327), right PTVR (r = − 0.357), and left PTVR (r = − 0.310), whereas no significant correlations were found in males (p > 0.05). In females, simple regression models based on right PV ®² = 8.8%) and right/left PTVR ®² = 11.0% and 7.7%) were significant. In the total sample, simple models were significant but weak ®² = 3.9–4.4%). No sex or side differences were detected (p > 0.05). Although CBCT-based volumetric parameters reflect age-related pulpal changes, they demonstrate limited standalone predictive value in this pediatric cohort. Nevertheless, their observed right–left symmetry and sex independence suggest they may serve as supportive biometric indicators within comprehensive forensic age estimation protocols requiring cautious interpretation.