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<p>Wilson disease (WD), a rare autosomal recessive hereditary disorder of copper metabolism that requires lifelong management and patient education. Short video platforms have become major channels for health information dissemination in China, but the quality and reliability of content related to Wilson disease on these platforms have not been systematically evaluated. A cross-sectional study design was adopted, and a total of 153 short videos related to Wilson disease were collected from three platforms: Bilibili, Douyin, and Kuaishou. On January 18, 2026, information quality and reliability assessment was conducted over two days using three validated evaluation tools: GQS for quality assessment, and the mDISCERN and JAMA benchmarks for reliability assessment. Meanwhile, user interaction indicators and video characteristics were extracted. Chi-square test, Kruskal–Wallis H test, and Spearman correlation analysis were used for statistical analysis. Videos on Bilibili achieved the highest scores in all three evaluations: GQS (3.34 ± 1.34), mDISCERN (2.84 ± 1.31), and JAMA (2.34 ± 1.24), followed by Douyin and Kuaishou. Among video creators, science communicators had the highest video scores (GQS: 4.40 ± 0.55), rather than health professionals (GQS: 2.91 ± 1.08). Videos with comprehensive themes covering “etiology, symptoms, and treatment” had higher quality scores (GQS 3.45 ± 1.17) and user interaction indicators than those with single themes. There was no correlation between video quality and interaction indicators, but a certain correlation existed between video quality and video duration. There are significant differences in the quality of content related to Wilson disease across different short video platforms, with Bilibili providing the most reliable information. Uploads by health professionals and comprehensive theme content are associated with higher information quality. Measures should be formulated according to the characteristics of different platforms to promote credible health information on Wilson disease, so as to assist patient education.</p>

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A cross-sectional analysis of the quality and reliability of Wilson disease videos on Bilibili, Douyin, and Kuaishou

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月4日

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  • Zhonghan Xu,
  • Yuchun Liu,
  • Zhaoquan Ma,
  • Shiqi Wen,
  • Haoming Chen,
  • Jun Huang,
  • Lingli Li,
  • Kaisheng Lin,
  • Junbing He

摘要

Wilson disease (WD), a rare autosomal recessive hereditary disorder of copper metabolism that requires lifelong management and patient education. Short video platforms have become major channels for health information dissemination in China, but the quality and reliability of content related to Wilson disease on these platforms have not been systematically evaluated. A cross-sectional study design was adopted, and a total of 153 short videos related to Wilson disease were collected from three platforms: Bilibili, Douyin, and Kuaishou. On January 18, 2026, information quality and reliability assessment was conducted over two days using three validated evaluation tools: GQS for quality assessment, and the mDISCERN and JAMA benchmarks for reliability assessment. Meanwhile, user interaction indicators and video characteristics were extracted. Chi-square test, Kruskal–Wallis H test, and Spearman correlation analysis were used for statistical analysis. Videos on Bilibili achieved the highest scores in all three evaluations: GQS (3.34 ± 1.34), mDISCERN (2.84 ± 1.31), and JAMA (2.34 ± 1.24), followed by Douyin and Kuaishou. Among video creators, science communicators had the highest video scores (GQS: 4.40 ± 0.55), rather than health professionals (GQS: 2.91 ± 1.08). Videos with comprehensive themes covering “etiology, symptoms, and treatment” had higher quality scores (GQS 3.45 ± 1.17) and user interaction indicators than those with single themes. There was no correlation between video quality and interaction indicators, but a certain correlation existed between video quality and video duration. There are significant differences in the quality of content related to Wilson disease across different short video platforms, with Bilibili providing the most reliable information. Uploads by health professionals and comprehensive theme content are associated with higher information quality. Measures should be formulated according to the characteristics of different platforms to promote credible health information on Wilson disease, so as to assist patient education.