Scholarlink

<p>Dysphagia is a recognized complication of Sjögren’s syndrome (SS) that can affect quality of life. In this cross-sectional study, we evaluated dysphagia-related quality of life and its associated factors in Chinese patients with SS. A total of 231 patients diagnosed with SS were enrolled. Dysphagia-related quality of life was assessed using the MD Anderson Dysphagia Inventory (MDADI), with a cutoff score of &lt; 60 defining impaired dysphagia-related quality of life as a patient-reported outcome measure. Additional assessments included the Fatigue Severity Scale (FSS), Visual Analog Scale (VAS) for pain, Oral Health Impact Profile-14 (OHIP-14), Pittsburgh Sleep Quality Index (PSQI), and Hospital Anxiety and Depression Scale (HADS). Laboratory analyses included C-reactive protein and erythrocyte sedimentation rate (ESR). The mean total MDADI score was 71.46 ± 17.83, and 22.9% of patients reported impaired dysphagia-related quality of life (MDADI &lt; 60). In multivariable analysis, the following factors were significantly associated with impaired dysphagia-related quality of life: poorer oral health (OR: 1.073; 95% CI: 1.033–1.114; <i>p</i> &lt; 0.001), higher anxiety levels (OR: 1.245; 95% CI: 1.113–1.393; <i>p</i> &lt; 0.001), greater fatigue severity (OR: 1.033; 95% CI: 1.002–1.065; <i>p</i> = 0.036), and elevated ESR (OR: 1.020; 95% CI: 1.003–1.038; <i>p</i> = 0.018). Impaired dysphagia-related quality of life was reported by 22.9% of Chinese patients with SS in this sample. The factors identified as independently associated with this outcome—including poorer oral health, elevated ESR, greater fatigue, and higher anxiety levels—may inform clinical awareness and guide future research.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

A cross-sectional study on dysphagia-related quality of life and its associated factors in chinese patients with sjögren’s syndrome

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年3月25日

查看全文
  • Lanlan Zhou,
  • Yifan Tang,
  • Binxiu Sha,
  • Zhenyu Li

摘要

Dysphagia is a recognized complication of Sjögren’s syndrome (SS) that can affect quality of life. In this cross-sectional study, we evaluated dysphagia-related quality of life and its associated factors in Chinese patients with SS. A total of 231 patients diagnosed with SS were enrolled. Dysphagia-related quality of life was assessed using the MD Anderson Dysphagia Inventory (MDADI), with a cutoff score of < 60 defining impaired dysphagia-related quality of life as a patient-reported outcome measure. Additional assessments included the Fatigue Severity Scale (FSS), Visual Analog Scale (VAS) for pain, Oral Health Impact Profile-14 (OHIP-14), Pittsburgh Sleep Quality Index (PSQI), and Hospital Anxiety and Depression Scale (HADS). Laboratory analyses included C-reactive protein and erythrocyte sedimentation rate (ESR). The mean total MDADI score was 71.46 ± 17.83, and 22.9% of patients reported impaired dysphagia-related quality of life (MDADI < 60). In multivariable analysis, the following factors were significantly associated with impaired dysphagia-related quality of life: poorer oral health (OR: 1.073; 95% CI: 1.033–1.114; p < 0.001), higher anxiety levels (OR: 1.245; 95% CI: 1.113–1.393; p < 0.001), greater fatigue severity (OR: 1.033; 95% CI: 1.002–1.065; p = 0.036), and elevated ESR (OR: 1.020; 95% CI: 1.003–1.038; p = 0.018). Impaired dysphagia-related quality of life was reported by 22.9% of Chinese patients with SS in this sample. The factors identified as independently associated with this outcome—including poorer oral health, elevated ESR, greater fatigue, and higher anxiety levels—may inform clinical awareness and guide future research.