Scholarlink

<p>Approximately 20% of infertility cases have a genetic origin. Preimplantation genetic testing (PGT) is an early prenatal diagnostic tool to prevent genetic disorders through embryo selection. Given its complexity, PGT requires a multidisciplinary approach, including psychosocial support, as infertility impacts mental health and overall well-being. Patients undergoing PGT often face prior miscarriages or IVF failures, elevating negative emotions and reducing quality of life. To compare affect levels, need for parenthood, and quality of life in IVF patients with and without PGT indications. This observational cross-sectional study included 375 patients divided into ‘PGT’ (n = 73) and ‘non-PGT’ (<i>n</i> = 302) groups. Participants completed the Positive and Negative Affect Schedule (PANAS), Need for Parenthood scale, and Fertility Quality of Life tool (FERTIQOL). Group comparisons were conducted. The groups did not differ in terms of gender, type and cause of infertility, and psychotropic medication use. The PGT group reported higher negative emotions, lower quality of life compared to the non-PGT group. Both groups showed high levels of need for parenthood. Patients indicated for PGT require greater support and monitoring, experiencing a significant emotional impact from the outset of treatment.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

The impact of preimplantation genetic testing on the quality of life of people undergoing assisted reproduction treatment

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年3月23日

查看全文
  • Maria Alciene Saraiva de Souza,
  • Erik Montagna,
  • Caio Parente Barbosa,
  • Bianca Bianco,
  • Victor Zaia

摘要

Approximately 20% of infertility cases have a genetic origin. Preimplantation genetic testing (PGT) is an early prenatal diagnostic tool to prevent genetic disorders through embryo selection. Given its complexity, PGT requires a multidisciplinary approach, including psychosocial support, as infertility impacts mental health and overall well-being. Patients undergoing PGT often face prior miscarriages or IVF failures, elevating negative emotions and reducing quality of life. To compare affect levels, need for parenthood, and quality of life in IVF patients with and without PGT indications. This observational cross-sectional study included 375 patients divided into ‘PGT’ (n = 73) and ‘non-PGT’ (n = 302) groups. Participants completed the Positive and Negative Affect Schedule (PANAS), Need for Parenthood scale, and Fertility Quality of Life tool (FERTIQOL). Group comparisons were conducted. The groups did not differ in terms of gender, type and cause of infertility, and psychotropic medication use. The PGT group reported higher negative emotions, lower quality of life compared to the non-PGT group. Both groups showed high levels of need for parenthood. Patients indicated for PGT require greater support and monitoring, experiencing a significant emotional impact from the outset of treatment.