Scholarlink

<p>Although toxocariasis has been considered a common and important neglected zoonotic parasitic disease worldwide, serologic ownership risk and owner-dog concomitant ophthalmic assessment remain to be fully established. Meanwhile, high toxocariasis prevalence has been recently found in seashore areas of southern Brazil. Accordingly, the present study aimed to perform owner serologic, fecal/hair dog, and owner- dog ophthalmic assessment in an endemic seashore area of southern Brazil. In overall, 112/342 (32.75%) owners were seropositive to anti-<i>Toxocara</i> spp. IgG antibodies by ELISA, with family income statistically significant (<i>p</i> = 0.007) as associated risk factor in the univariate analysis. In addition, <i>Toxocara</i> spp. eggs were visualized in only 6/216 (2.78%) dog feces and 5/236 (2.12%) dog hair samples. Logistic regression indicated that untreated water increased 6.3-fold the dog likelihood for <i>T. canis</i> eggs in hair or feces, while purebred dogs and outdoor access were considered as associated protective factors. Only one/342 individual presented highly suggestive ocular toxocariasis, in one eye and at the cicatricial stage (seropositive for anti-<i>Toxocara</i> IgG antibodies). Out of an additional 32 individuals with some degree of retinal scarring compatible with prior chorioretinitis, 10/32 (31.3%) were also seropositive for anti-<i>Toxocara</i> IgG antibodies. In addition, ophthalmic abnormalities were identified in 205/237 (86.5%) examined dogs, with the most frequent findings involving various nonspecific chronic lesions in 177/237 (74.7%), followed by Florida Spot Keratopathy (FSK) in 12/237 (5.1%) and retinopathy in 11/237 (4.6%) dogs. FSK prevalence in dogs was considered very high. Although less prevalent, fundoscopic changes were significantly associated with <i>Toxocara</i> spp. in both owners and their dogs. In conclusion, similar ophthalmologic abnormalities associated with shared environmental exposure to <i>Toxocara</i> spp. have highlighted the importance of One Health approach for holistic interpretation of human-dog natural occurrence of toxocariasis.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

One Health approach on toxocariasis and ophthalmic assessment in owners and dogs

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月24日

查看全文
  • Mariana Bolzani Bach,
  • Louise Bach Kmetiuk,
  • Aaronson Ramathan Freitas,
  • Bianca Luiza Valduga Guareschi,
  • Isabella Braghin Ferreira,
  • Roberto Teixeira de Souza Filho,
  • Gabriela Rodrigues e Fonseca,
  • Fernanda Muraro de Alvarenga,
  • Ruana Renosto Delai,
  • Claudia Turra Pimpão,
  • João Henrique Perotta,
  • Ivan Roque de Barros Filho,
  • Rogério Giuffrida,
  • Susana Angélica Zevallos Lescano,
  • Karin Regina Luhm,
  • Fabiano Borges Figueiredo,
  • Camila Girardi Fachin,
  • Fabiano Montiani-Ferreira,
  • Vamilton Alvares Santarém,
  • Alexander Welker Biondo,
  • Denise Siqueira de Carvalho

摘要

Although toxocariasis has been considered a common and important neglected zoonotic parasitic disease worldwide, serologic ownership risk and owner-dog concomitant ophthalmic assessment remain to be fully established. Meanwhile, high toxocariasis prevalence has been recently found in seashore areas of southern Brazil. Accordingly, the present study aimed to perform owner serologic, fecal/hair dog, and owner- dog ophthalmic assessment in an endemic seashore area of southern Brazil. In overall, 112/342 (32.75%) owners were seropositive to anti-Toxocara spp. IgG antibodies by ELISA, with family income statistically significant (p = 0.007) as associated risk factor in the univariate analysis. In addition, Toxocara spp. eggs were visualized in only 6/216 (2.78%) dog feces and 5/236 (2.12%) dog hair samples. Logistic regression indicated that untreated water increased 6.3-fold the dog likelihood for T. canis eggs in hair or feces, while purebred dogs and outdoor access were considered as associated protective factors. Only one/342 individual presented highly suggestive ocular toxocariasis, in one eye and at the cicatricial stage (seropositive for anti-Toxocara IgG antibodies). Out of an additional 32 individuals with some degree of retinal scarring compatible with prior chorioretinitis, 10/32 (31.3%) were also seropositive for anti-Toxocara IgG antibodies. In addition, ophthalmic abnormalities were identified in 205/237 (86.5%) examined dogs, with the most frequent findings involving various nonspecific chronic lesions in 177/237 (74.7%), followed by Florida Spot Keratopathy (FSK) in 12/237 (5.1%) and retinopathy in 11/237 (4.6%) dogs. FSK prevalence in dogs was considered very high. Although less prevalent, fundoscopic changes were significantly associated with Toxocara spp. in both owners and their dogs. In conclusion, similar ophthalmologic abnormalities associated with shared environmental exposure to Toxocara spp. have highlighted the importance of One Health approach for holistic interpretation of human-dog natural occurrence of toxocariasis.