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<p>Data transactions in healthcare are steadily increasing across various platforms, aiming to improve patient care and increase data transparency. Blockchain technology will serve as a catalyst in healthcare data transactions, ensuring data security and privacy for various stakeholders. Improving data security, transparency, and interoperability, blockchain technology’s application in healthcare has demonstrated considerable promise. However, healthcare applications that rely on real-time data transaction settlement face obstacles caused by Layer1 blockchains’ poor transaction throughput and excessive latency. In this work, we adopt established consensus and a zk-Rollup verification workflow, specifying healthcare-oriented configurations for security, auditability, and throughput. This paper integrates the smart contracts, zero knowledge proof and off chain data storage to increase the efficiency, and security and reduce transaction costs. The usefulness of the suggested algorithm in healthcare applications is demonstrated by thorough literature research, comparative analysis, and experimental data. Transaction throughput increases very high, latency improved by 57%, and decrease the transaction cost to 96% in healthcare data transactions which are all greatly improved by the proposed system. Unlike existing zk-Rollup–based healthcare frameworks, the proposed model integrates cross-chain identity validation and verifiable data provenance to achieve secure interoperability across multi-chain healthcare systems.</p>

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Secure, scalable, and interoperable healthcare data exchange using layer-2 ZK-rollups, smart contracts, and IPFS

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年1月24日

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  • Abhinav Raghav,
  • Aanjey Mani Tripathi,
  • Niyaz Ahmad Wani,
  • Naveed Ahmad,
  • Yasir Javed,
  • Mohamad Ladan

摘要

Data transactions in healthcare are steadily increasing across various platforms, aiming to improve patient care and increase data transparency. Blockchain technology will serve as a catalyst in healthcare data transactions, ensuring data security and privacy for various stakeholders. Improving data security, transparency, and interoperability, blockchain technology’s application in healthcare has demonstrated considerable promise. However, healthcare applications that rely on real-time data transaction settlement face obstacles caused by Layer1 blockchains’ poor transaction throughput and excessive latency. In this work, we adopt established consensus and a zk-Rollup verification workflow, specifying healthcare-oriented configurations for security, auditability, and throughput. This paper integrates the smart contracts, zero knowledge proof and off chain data storage to increase the efficiency, and security and reduce transaction costs. The usefulness of the suggested algorithm in healthcare applications is demonstrated by thorough literature research, comparative analysis, and experimental data. Transaction throughput increases very high, latency improved by 57%, and decrease the transaction cost to 96% in healthcare data transactions which are all greatly improved by the proposed system. Unlike existing zk-Rollup–based healthcare frameworks, the proposed model integrates cross-chain identity validation and verifiable data provenance to achieve secure interoperability across multi-chain healthcare systems.