Scholarlink

<p>Phosphorus-31 magnetic resonance spectroscopic imaging (<sup>31</sup>P-MRSI) provides valuable non-invasivein vivoinformation on tissue metabolism but is burdened by poor sensitivity and prolonged scan duration. Ultra-short echo time (UTE) acquisitions minimize signal loss when probing signals with relatively short spin-spin relaxation time (T<sub>2</sub>), while also preventing first-order dephasing. Here, a three-dimensional (3D) UTE sequence with a rosette k-space trajectory (PETALUTE) is applied to <sup>31</sup>P-MRSI at 3T. Conventional weighted MRSI employs highly regular Cartesian k-space sampling, susceptible to substantial artifacts when accelerated via undersampling. In contrast, this novel sequence’s “petal-like” pattern offers incoherent sampling more suitable for compressed sensing (CS). These results showcase the competitive performance of PETALUTE against conventional weighted <sup>31</sup>P-MRSI with simulation, phantom, and in vivo leg muscle comparisons.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Feasibility and comparison of 3D modified rosette ultra-short echo time (PETALUTE) with conventional weighted acquisition in 31P-MRSI

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年2月22日

查看全文
  • Brian Bozymski,
  • Xin Shen,
  • Ali Özen,
  • Mark Chiew,
  • M. Albert Thomas,
  • William T. Clarke,
  • Stephen Sawiak,
  • Ulrike Dydak,
  • Uzay Emir

摘要

Phosphorus-31 magnetic resonance spectroscopic imaging (31P-MRSI) provides valuable non-invasivein vivoinformation on tissue metabolism but is burdened by poor sensitivity and prolonged scan duration. Ultra-short echo time (UTE) acquisitions minimize signal loss when probing signals with relatively short spin-spin relaxation time (T2), while also preventing first-order dephasing. Here, a three-dimensional (3D) UTE sequence with a rosette k-space trajectory (PETALUTE) is applied to 31P-MRSI at 3T. Conventional weighted MRSI employs highly regular Cartesian k-space sampling, susceptible to substantial artifacts when accelerated via undersampling. In contrast, this novel sequence’s “petal-like” pattern offers incoherent sampling more suitable for compressed sensing (CS). These results showcase the competitive performance of PETALUTE against conventional weighted 31P-MRSI with simulation, phantom, and in vivo leg muscle comparisons.