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<p>This study introduces a 2-D Photonic Crystal (PhC) biosensor designed, simulated, and evaluated for detecting glucose concentrations in urine by utilizing refractive index variations. The sensor demonstrates exceptional performance, achieving a sensitivity of 20,040.30&#xa0;nm/RIU for glucose levels ranging from 0–15&#xa0;mg/dl, a quality factor of 10,424.55, and a detection limit as low as 8 × 10<sup>−10</sup>, surpassing benchmarks reported in the literature. With compact dimensions of 16.8 × 17.6 µm<sup>2</sup> and compatibility with modern fabrication techniques, the proposed design is well suited for integration into portable diagnostic devices. A comprehensive comparative analysis underscores its superior sensitivity, ultra-high quality factor, and compact design, establishing it as a major advancement in glucose detection technology.</p>

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A Compact 2-D photonic crystal biomedical sensor for enhanced glucose concentration detection in urine

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年2月10日

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  • Mahmoud M. Hamed,
  • Nazmi A. Mohammed,
  • Kareem A. Badawi

摘要

This study introduces a 2-D Photonic Crystal (PhC) biosensor designed, simulated, and evaluated for detecting glucose concentrations in urine by utilizing refractive index variations. The sensor demonstrates exceptional performance, achieving a sensitivity of 20,040.30 nm/RIU for glucose levels ranging from 0–15 mg/dl, a quality factor of 10,424.55, and a detection limit as low as 8 × 10−10, surpassing benchmarks reported in the literature. With compact dimensions of 16.8 × 17.6 µm2 and compatibility with modern fabrication techniques, the proposed design is well suited for integration into portable diagnostic devices. A comprehensive comparative analysis underscores its superior sensitivity, ultra-high quality factor, and compact design, establishing it as a major advancement in glucose detection technology.