<p>The Maisotsenko cycle-based coolers have gained increasing attention in recent years due to their advantages of low energy consumption and environmental friendliness. Optimizing the model structure and operating conditions is the primary approach for enhancing the cooling performance of dew-point evaporation systems. In this paper, a novel mathematical model of the perforated dew-point evaporative cooler was developed to investigate its cooling performance. The key findings that emerged from this investigation were: (1) Both perforated and non-perforated dew-point evaporative cooling systems exhibited similar trends in relation to the impact of model size and inlet air parameters. (2) The performance of the dew-point evaporative cooler could be enhanced by implementing the perforation method when the total supply air ratio is below 0.5, and optimal performance was achieved with a single-perforation design. (3) The outlet temperature of the dry channel initially showed a downward trend when the supply air ratio was 0.3, and subsequently gradually increased with an elevated supply air ratio. It is worth noting that within the range of 0.5 to 0.6 for the supply air ratio, the minimum outlet air temperature was achieved.</p>