<p>Across all fields, experts strive to collect and analyze numerous data to extract meaningful insight. In response to this trend, Hadoop and Spark have emerged, and many organizations have adopted these platforms for big data storage and processing. In addition, data centers with powerful servers are constantly expanding to accommodate the increasing number of data, causing significant costs and environmental problems due to the tremendous energy consumption. Single board computer (SBC) clusters have emerged as a promising alternative for efficient computing. Most SBCs have adopted a microSD slot for data storage; thus effectively processing massive data has some limitations. However, the latest generation Raspberry Pi (RPi), model 5B provides a peripheral component interconnect express (PCIe) interface, enabling high-performance storage media, such as solid state drives (SSD). This paper extensively investigates the practicability and potential of SBCs for terabyte-scale big data processing. We build the SBC Hadoop cluster, adopting the most powerful, latest RPi 5B (8 GB of RAM) with a fast PCIe-based SSD via the PCIe interface, and perform six widely known benchmarks with a large (up to 2 TB) data size. Furthermore, this paper discusses challenges and suggestions, including the effects of input/output (I/O) throughput, central processing unit (CPU) overclocking, power supply, and trim command, which significantly affect SBC Hadoop performance. This comprehensive study concludes that integrating the enhanced computing of RPi 5B with unlocked I/O performance finally paves the way for a practical solution to real-world big data processing on SBC clusters.</p>