<p>In cases of progressive idiopathic pleuroparenchymal fibroelastosis (iPPFE), the entire lung is suspended above the thorax. This causes the tracheal bifurcation to elevate upward and the trachea to meander. In this study, we aimed to investigate the association between tracheal meandering and the prognosis of iPPFE. We retrospectively collected data from 41 patients diagnosed with iPPFE between April 2009 and December 2021 and evaluated chest radiograph at the diagnosis of iPPFE. The angle and length/height cutoff values were 23° and 63&#xa0;mm/m, respectively. The median survival time (MST) was significantly longer in patients with an angle of 23° or less (89&#xa0;months) than in those with an angle over 23° (24&#xa0;months). The MST was also significantly shorter in patients with a length/height of 63&#xa0;mm/m or less (33&#xa0;months) than in those over 63&#xa0;mm/m (89&#xa0;months). Multivariate analysis did not show a statistically significant association between the angle and death within 24&#xa0;months; however, a possible trend was observed. In conclusion, calculating tracheal excursion using only chest radiograph is a straightforward process that may be useful in predicting the prognosis of iPPFE.</p>

错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

Tracheal meandering may predict prognosis in idiopathic pleuroparenchymal fibroelastosis: a retrospective observational study

  • Motoyasu Kato,
  • Haruki Hirakawa,
  • Eri Hayakawa,
  • Haruhiko Hirano,
  • Chisato Tadokoro,
  • Makiko Kohmaru,
  • Takashi Akimoto,
  • Soichiro Soma,
  • Shunichi Kataoka,
  • Yuta Arai,
  • Shun Nakazawa,
  • Hiroaki Motomura,
  • Takuto Sueyasu,
  • Yusuke Ochi,
  • Issei Sumiyoshi,
  • Junko Watanabe,
  • Kotaro Kadoya,
  • Hiroaki Ihara,
  • Shinsaku Togo,
  • Shinichi Sasaki,
  • Kazuhisa Takahashi

摘要

In cases of progressive idiopathic pleuroparenchymal fibroelastosis (iPPFE), the entire lung is suspended above the thorax. This causes the tracheal bifurcation to elevate upward and the trachea to meander. In this study, we aimed to investigate the association between tracheal meandering and the prognosis of iPPFE. We retrospectively collected data from 41 patients diagnosed with iPPFE between April 2009 and December 2021 and evaluated chest radiograph at the diagnosis of iPPFE. The angle and length/height cutoff values were 23° and 63 mm/m, respectively. The median survival time (MST) was significantly longer in patients with an angle of 23° or less (89 months) than in those with an angle over 23° (24 months). The MST was also significantly shorter in patients with a length/height of 63 mm/m or less (33 months) than in those over 63 mm/m (89 months). Multivariate analysis did not show a statistically significant association between the angle and death within 24 months; however, a possible trend was observed. In conclusion, calculating tracheal excursion using only chest radiograph is a straightforward process that may be useful in predicting the prognosis of iPPFE.