Scholarlink

<p>China has the largest number of hepatitis B patients globally, making early detection, intervention, and treatment crucial. This study assessed the knowledge, attitude, and practice (KAP) toward antiviral treatment among chronic hepatitis B (CHB) patients. A web-based cross-sectional study was conducted among hepatitis B patients at the author’s Hospital, Tianjin, China, between October 2022 and January 2023. Primary outcomes were KAP scores (knowledge: 0–18, attitude: 0–35, practice: 0–50). Secondary outcomes included factors associated with KAP. A total of 457 hepatitis B patients participated. The Mean KAP scores were 9.70 ± 4.64 (knowledge), 24.00 ± 3.28 (attitude), and 38.85 ± 6.56 (practice). Factors independently associated with adequate knowledge included household income 5,000–10,000 CNY (OR = 1.81, 95%CI: 1.05–3.12; positive factor), &gt; 10,000 CNY (OR = 2.05, 95%CI: 1.01–4.17; positive factor), rural cooperative medical insurance (OR = 0.5, 95%CI: 0.27–0.94; negative factor), carrier-stage hepatitis B (OR = 0.34, 95%CI: 0.13–0.91; negative factor), and treatment &gt; 10 years (OR = 2.74, 95%CI: 1.09–6.88; positive factor). Positive attitude was associated with income &gt; 10,000 CNY (OR = 2.77, 95%CI: 1.41–5.44; positive factor) but negatively with cirrhosis (OR = 0.43, 95%CI: 0.24–0.76; negative factor) and liver cancer (OR = 0.19, 95%CI: 0.05–0.71; negative factor). Knowledge (OR = 1.20, 95%CI: 1.13–1.27) was independently associated with a proactive practice, while female sex (OR = 0.58, 95%CI: 0.35–0.95) and use to drink (OR = 0.43, 95% CI: 0.22–0.82) were independently associated with worse practice. CHB patients demonstrated suboptimal KAP levels regarding antiviral therapy. Policy support should prioritize low-income populations to improve treatment adherence and outcomes.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Knowledge, attitude, and practice toward antiviral treatment of chronic hepatitis B among patients

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年10月28日

查看全文
  • Hong Zhang,
  • Sen Tao,
  • Chunyan Wang,
  • Huan Liu,
  • Li Zhou,
  • Hongwu Wang,
  • Jia Li

摘要

China has the largest number of hepatitis B patients globally, making early detection, intervention, and treatment crucial. This study assessed the knowledge, attitude, and practice (KAP) toward antiviral treatment among chronic hepatitis B (CHB) patients. A web-based cross-sectional study was conducted among hepatitis B patients at the author’s Hospital, Tianjin, China, between October 2022 and January 2023. Primary outcomes were KAP scores (knowledge: 0–18, attitude: 0–35, practice: 0–50). Secondary outcomes included factors associated with KAP. A total of 457 hepatitis B patients participated. The Mean KAP scores were 9.70 ± 4.64 (knowledge), 24.00 ± 3.28 (attitude), and 38.85 ± 6.56 (practice). Factors independently associated with adequate knowledge included household income 5,000–10,000 CNY (OR = 1.81, 95%CI: 1.05–3.12; positive factor), > 10,000 CNY (OR = 2.05, 95%CI: 1.01–4.17; positive factor), rural cooperative medical insurance (OR = 0.5, 95%CI: 0.27–0.94; negative factor), carrier-stage hepatitis B (OR = 0.34, 95%CI: 0.13–0.91; negative factor), and treatment > 10 years (OR = 2.74, 95%CI: 1.09–6.88; positive factor). Positive attitude was associated with income > 10,000 CNY (OR = 2.77, 95%CI: 1.41–5.44; positive factor) but negatively with cirrhosis (OR = 0.43, 95%CI: 0.24–0.76; negative factor) and liver cancer (OR = 0.19, 95%CI: 0.05–0.71; negative factor). Knowledge (OR = 1.20, 95%CI: 1.13–1.27) was independently associated with a proactive practice, while female sex (OR = 0.58, 95%CI: 0.35–0.95) and use to drink (OR = 0.43, 95% CI: 0.22–0.82) were independently associated with worse practice. CHB patients demonstrated suboptimal KAP levels regarding antiviral therapy. Policy support should prioritize low-income populations to improve treatment adherence and outcomes.