<p>This paper presents a novel deep learning approach for the adaptive fusion of multicultural visual elements in cross-cultural visual communication design for interface development. We address the challenge of creating culturally appropriate digital interfaces by developing a comprehensive framework that combines convolutional neural networks, attention mechanisms, and generative adversarial networks to analyze, extract, and adaptively fuse cultural features from diverse visual communication design elements. The proposed algorithm dynamically adjusts color schemes, spatial arrangements, typography, and iconography based on target cultural preferences while maintaining visual communication design coherence and functional clarity. Experimental evaluations conducted across five cultural regions demonstrate that our approach outperforms existing methods in cultural appropriateness (17.3% improvement), aesthetic coherence (12.8% enhancement), and user satisfaction (27.3% increase). Implementation in e-commerce, educational, and financial service applications showed significant improvements in user engagement, task efficiency, and conversion rates. Our research contributes to the advancement of inclusive digital experiences by providing a computational framework for cross-cultural visual communication design that respects cultural diversity while enhancing user experience across cultural boundaries.</p>