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<p>Domestic yaks are a crucial livestock species on the Qinghai-Tibet Plateau and its surrounding regions, providing indispensable resources for local residents’ livelihoods and production. China harbors the world’s largest yak population and possesses exceptionally rich yak genetic resources. In this study, we performed whole-genome resequencing on 200 individuals representing 19 indigenous yak breeds. Sequencing of DNA samples generated approximately 4.3 terabytes (TB) of raw data, with an average sequencing depth of 8.36×. High-quality sequencing reads were successfully mapped to the reference yak genome, achieving an average alignment rate of 98.4%. Following stringent quality control and filtering, we identified a total of 13.41 million high-confidence single nucleotide polymorphisms (SNPs). These genome-wide SNP markers provide a valuable resource for in-depth investigation into the demographic history and adaptive evolutionary mechanisms of Chinese yak populations, offering critical genomic support for the conservation and innovative utilization of yak genetic resources.</p>

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Whole-genome resequencing data of 200 domestic yaks from China

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年5月20日

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  • Bao Cai,
  • Lin Xiong,
  • Jie Pei,
  • Qianyun Ge,
  • Xian Guo

摘要

Domestic yaks are a crucial livestock species on the Qinghai-Tibet Plateau and its surrounding regions, providing indispensable resources for local residents’ livelihoods and production. China harbors the world’s largest yak population and possesses exceptionally rich yak genetic resources. In this study, we performed whole-genome resequencing on 200 individuals representing 19 indigenous yak breeds. Sequencing of DNA samples generated approximately 4.3 terabytes (TB) of raw data, with an average sequencing depth of 8.36×. High-quality sequencing reads were successfully mapped to the reference yak genome, achieving an average alignment rate of 98.4%. Following stringent quality control and filtering, we identified a total of 13.41 million high-confidence single nucleotide polymorphisms (SNPs). These genome-wide SNP markers provide a valuable resource for in-depth investigation into the demographic history and adaptive evolutionary mechanisms of Chinese yak populations, offering critical genomic support for the conservation and innovative utilization of yak genetic resources.