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<p>In the context of public health, asymptomatic carriers of respiratory infectious diseases are considered a hidden yet critical factor in the transmission of infection and represent a key target for efforts to mitigate disease spread. To contribute a unique genomic resource to the SARS-CoV-2 research community, we collected SARS-CoV-2–positive samples from asymptomatic individuals at the SB Coronavirus Inspection Center Corp. during the COVID-19 pandemic in Japan and conducted a comprehensive analysis of their viral genomes. Using Illumina COVIDSeq technology, we successfully generated 8,266 SARS-CoV-2 genome assemblies, all of which have been made publicly available to facilitate further research. In this report, we summarize our efforts to collect SARS-CoV-2–positive samples from asymptomatic individuals and highlight the key features and accessibility of this genomic dataset.</p>

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8,266 SARS-CoV-2 Genomic Assemblies from Asymptomatic Carriers in Japan

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月25日

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  • Hajime Ohyanagi,
  • Junko S. Takeuchi,
  • Yuichi Kawanishi,
  • Saya Ohi,
  • Teiichiro Shiino,
  • Moto Kimura,
  • Yusuke Takahashi,
  • Shigeru Yoshida,
  • Minoru Kato,
  • Yukumasa Kazuyama,
  • Masato Ikeda,
  • Wataru Sugiura

摘要

In the context of public health, asymptomatic carriers of respiratory infectious diseases are considered a hidden yet critical factor in the transmission of infection and represent a key target for efforts to mitigate disease spread. To contribute a unique genomic resource to the SARS-CoV-2 research community, we collected SARS-CoV-2–positive samples from asymptomatic individuals at the SB Coronavirus Inspection Center Corp. during the COVID-19 pandemic in Japan and conducted a comprehensive analysis of their viral genomes. Using Illumina COVIDSeq technology, we successfully generated 8,266 SARS-CoV-2 genome assemblies, all of which have been made publicly available to facilitate further research. In this report, we summarize our efforts to collect SARS-CoV-2–positive samples from asymptomatic individuals and highlight the key features and accessibility of this genomic dataset.