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<p><i>Chelidonium majus</i> is a herbaceous plant of significant medicinal value, which has been widely distributed in Europe, Asia, and Northern Africa. However, its genome remains uncharacterized. Herein, we present a high-quality chromosome-scale genome for <i>C. majus</i> with a size of 1.06 Gb, and 91.21% of the sequences anchored onto 6 chromosomes, comprising 1,520 contigs with an N50 of 106.65 Mb. The genome is predicted to contain 25,203 protein-coding genes, with 98.2% have been functional annotated. The completeness of the genome is highlighted by a BUSCO score of 97.6%. This high-quality genome assembly provides a vital resource for future gene screening, drug discovery, and pharmacological exploration in <i>C. majus</i>.</p>

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A chromosome-level genome assembly of the Chinese herbal medicine Chelidonium majus

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年10月14日

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  • Xialian Bu,
  • Xianqi Peng,
  • Jing Chen,
  • Lei Huang,
  • Chen Niu,
  • Yu Zhao,
  • Jian Zhu,
  • Xiaohong Huang,
  • Aqin Zheng,
  • Chiping Kong,
  • Huantao Qu,
  • Weijie Sun,
  • Jiayun Yao

摘要

Chelidonium majus is a herbaceous plant of significant medicinal value, which has been widely distributed in Europe, Asia, and Northern Africa. However, its genome remains uncharacterized. Herein, we present a high-quality chromosome-scale genome for C. majus with a size of 1.06 Gb, and 91.21% of the sequences anchored onto 6 chromosomes, comprising 1,520 contigs with an N50 of 106.65 Mb. The genome is predicted to contain 25,203 protein-coding genes, with 98.2% have been functional annotated. The completeness of the genome is highlighted by a BUSCO score of 97.6%. This high-quality genome assembly provides a vital resource for future gene screening, drug discovery, and pharmacological exploration in C. majus.