Scholarlink

<p>Ribosome-associated quality control (RQC) safeguards translation by detecting and resolving collided ribosomes and triaging their nascent chains. This Review outlines mechanisms, crosstalk and disease implications of RQC cascades and presents RQC as a ‘first responder’ that prevents escalation to global stress responses and provides protection against proteostasis collapse.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Ribosome-associated quality control and related mechanisms

  • 期刊论文

  • 发表日期：

    2026年3月17日

查看全文
  • Toshifumi Inada

摘要

Ribosome-associated quality control (RQC) safeguards translation by detecting and resolving collided ribosomes and triaging their nascent chains. This Review outlines mechanisms, crosstalk and disease implications of RQC cascades and presents RQC as a ‘first responder’ that prevents escalation to global stress responses and provides protection against proteostasis collapse.