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<p>Influenza, a major “One Health” threat, has gained heightened attention following recent reports of highly pathogenic avian influenza in dairy cattle and cow-to-human transmission in the USA. This review explores general aspects of influenza A virus (IAV) biology, its interactions with mammalian hosts, and discusses the key considerations for developing vaccines to prevent or curtail IAV infection in the bovine mammary gland and its spread through milk.</p>

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Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年1月14日

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  • Rodrigo Prado Martins,
  • Daniel Marc,
  • Pierre Germon,
  • Sascha Trapp,
  • Ignacio Caballero-Posadas

摘要

Influenza, a major “One Health” threat, has gained heightened attention following recent reports of highly pathogenic avian influenza in dairy cattle and cow-to-human transmission in the USA. This review explores general aspects of influenza A virus (IAV) biology, its interactions with mammalian hosts, and discusses the key considerations for developing vaccines to prevent or curtail IAV infection in the bovine mammary gland and its spread through milk.