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<p>The escalating global environmental crisis demands transformative biotechnological solutions that are both sustainable and scalable. This perspective advocates Data-Driven Synthetic Microbes (DDSM); engineered microorganisms designed through integrating omics, machine learning, and systems biology to tackle challenges like PFAS degradation, greenhouse gas mitigation, and sustainable biomanufacturing. DDSMs offer a rational framework for developing robust microbial systems, reshaping the future of synthetic biology toward environmental resilience and circular bioeconomy.</p>

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Data-driven synthetic microbes for sustainable future

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月7日

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  • Iqra Mariam,
  • Ulrika Rova,
  • Paul Christakopoulos,
  • Leonidas Matsakas,
  • Alok Patel

摘要

The escalating global environmental crisis demands transformative biotechnological solutions that are both sustainable and scalable. This perspective advocates Data-Driven Synthetic Microbes (DDSM); engineered microorganisms designed through integrating omics, machine learning, and systems biology to tackle challenges like PFAS degradation, greenhouse gas mitigation, and sustainable biomanufacturing. DDSMs offer a rational framework for developing robust microbial systems, reshaping the future of synthetic biology toward environmental resilience and circular bioeconomy.