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<p>This work introduces a realization of a proportional-integral-derivative-acceleration control scheme as a chemical reaction network governed by mass action kinetics. A central feature of this architecture is a speed and acceleration biosensing mechanism integrated into a feedback configuration. Our control scheme provides enhanced dynamic performance and robust steady-state tracking. In addition to our theoretical analysis, this is practically highlighted in-silico in both the deterministic and stochastic settings.</p>

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Biochemical implementation of acceleration sensing and PIDA control

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年4月26日

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  • Emmanouil Alexis,
  • Sebastián Espinel-Ríos,
  • Ioannis G. Kevrekidis,
  • José L. Avalos

摘要

This work introduces a realization of a proportional-integral-derivative-acceleration control scheme as a chemical reaction network governed by mass action kinetics. A central feature of this architecture is a speed and acceleration biosensing mechanism integrated into a feedback configuration. Our control scheme provides enhanced dynamic performance and robust steady-state tracking. In addition to our theoretical analysis, this is practically highlighted in-silico in both the deterministic and stochastic settings.