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<p>Neuromodulation therapy comprises a range of non-destructive and adjustable methods for modulating neural activity using electrical stimulations, chemical agents, or mechanical interventions. Here, we discuss how electrophysiological brain recording and imaging at multiple scales, from cells to large-scale brain networks, contribute to defining the target location and stimulation parameters of neuromodulation, with an emphasis on deep brain stimulation (DBS).</p>

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Electrophysiological approaches to informing therapeutic interventions with deep brain stimulation

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年1月20日

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  • Atefeh Asadi,
  • Alex I. Wiesman,
  • Christoph Wiest,
  • Sylvain Baillet,
  • Huiling Tan,
  • Muthuraman Muthuraman

摘要

Neuromodulation therapy comprises a range of non-destructive and adjustable methods for modulating neural activity using electrical stimulations, chemical agents, or mechanical interventions. Here, we discuss how electrophysiological brain recording and imaging at multiple scales, from cells to large-scale brain networks, contribute to defining the target location and stimulation parameters of neuromodulation, with an emphasis on deep brain stimulation (DBS).