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<p>Spaceflight-associated neuro-ocular syndrome (SANS) poses a significant risk for astronauts, being linked to intracranial pressure (ICP) changes in microgravity. Investigating ICP in space has been challenging. We evaluated a telemetric lumbar ICP monitoring system that shows promise for investigating microgravity-induced intracranial pressure changes in astronauts. Despite limitations in pulse amplitude analysis and pressure underestimation, the system’s long-term stability and overall performance support its recommendation for SANS research in space.</p>

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Telemetric lumbar cerebrospinal fluid pressure monitoring for spaceflight: a novel approach to spaceflight-associated neuro-ocular syndrome research

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年5月7日

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  • Anders Eklund,
  • Tomas Bäcklund,
  • Michael A. Williams,
  • Jan Malm

摘要

Spaceflight-associated neuro-ocular syndrome (SANS) poses a significant risk for astronauts, being linked to intracranial pressure (ICP) changes in microgravity. Investigating ICP in space has been challenging. We evaluated a telemetric lumbar ICP monitoring system that shows promise for investigating microgravity-induced intracranial pressure changes in astronauts. Despite limitations in pulse amplitude analysis and pressure underestimation, the system’s long-term stability and overall performance support its recommendation for SANS research in space.