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<p>Breast cancer is a heterogeneous disease with global reach. Basigin (BSG) is a transmembrane protein with multifunctional roles in the breast tumor microenvironment. Using the hallmarks of cancer, we explore the pleiotropic roles of BSG in breast cancer. Further, we examine the cellular interactants of BSG and the molecular regulators of BSG. BSG has the potential to play a prognostic role and is a candidate target for new therapeutic interventions.</p>

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The pleiotropic roles of non-hormonal receptor basigin and regulatory microRNAs in breast cancer

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年9月29日

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  • Kelsey Bruce,
  • Michael Kerin,
  • Vinitha Richard

摘要

Breast cancer is a heterogeneous disease with global reach. Basigin (BSG) is a transmembrane protein with multifunctional roles in the breast tumor microenvironment. Using the hallmarks of cancer, we explore the pleiotropic roles of BSG in breast cancer. Further, we examine the cellular interactants of BSG and the molecular regulators of BSG. BSG has the potential to play a prognostic role and is a candidate target for new therapeutic interventions.