<p>This study characterizes trends in contralateral breast cancer (CBC) and contralateral prophylactic mastectomy (CPM) in Ontario, Canada, by breast cancer risk level. Overall, there has been a decline in CBC rates and the concomitant rise in CPM rates after unilateral breast cancer diagnosis, largely driven by <i>high-risk</i> individuals. Considerations for breast cancer risk level are recommended in evaluations of CBC and CPM trends.</p>

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Trends in contralateral breast cancer and contralateral prophylactic mastectomy from 2009 to 2016

  • Shana J. Kim,
  • Jasleen Arneja,
  • Rebecca A. G. Christensen,
  • Geoff M. Anderson,
  • Jennifer D. Brooks

摘要

This study characterizes trends in contralateral breast cancer (CBC) and contralateral prophylactic mastectomy (CPM) in Ontario, Canada, by breast cancer risk level. Overall, there has been a decline in CBC rates and the concomitant rise in CPM rates after unilateral breast cancer diagnosis, largely driven by high-risk individuals. Considerations for breast cancer risk level are recommended in evaluations of CBC and CPM trends.