Scholarlink

<p>Celery (<i>Apium graveolens</i>) is a globally cultivated vegetable renowned for its health-promoting and nutraceutical benefits. Exploring its genomic and metabolic diversity can help to facilitate breeding selection. Here, by integrating genomic and metabolomic analyses of 305 globally representative accessions, we reveal pronounced east–west population structure that parallels geographical distribution and varietal differentiation, with three major variety groups showing distinct domestication trajectories. We identify key loci associated with domestication-related traits, including petiole morphology and bolting time. Metabolite profiling uncovers divergence among populations: var. dulce, predominantly consumed raw in Western culinary traditions, exhibits marked reductions in bitter coumarins and alkaloids—a metabolic signature consistent with fresh-eating preferences. Metabolite GWAS map 335,692 loci for 1552 metabolites. We develop genomic prediction models for metabolite abundance to aid breeding. Collectively, our study reveals the genomic and metabolic landscape of celery domestication, and provides hypotheses regarding how cultural practices, alongside regional environmental factors, may have jointly shaped current diversity.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

East-west divergence and metabolic differentiation in celery domestication

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年7月31日

查看全文
  • Chenhao Wang,
  • Mengyi Zhang,
  • Qinglong Xu,
  • Xiangyang Du,
  • Jianeng Che,
  • Kuangtian Xu,
  • Lei Ge,
  • Xiao Li,
  • Zhongyuan Hu,
  • Jinghua Yang,
  • Xinsheng Wu,
  • Mingfang Zhang,
  • Xiaolong Lyu

摘要

Celery (Apium graveolens) is a globally cultivated vegetable renowned for its health-promoting and nutraceutical benefits. Exploring its genomic and metabolic diversity can help to facilitate breeding selection. Here, by integrating genomic and metabolomic analyses of 305 globally representative accessions, we reveal pronounced east–west population structure that parallels geographical distribution and varietal differentiation, with three major variety groups showing distinct domestication trajectories. We identify key loci associated with domestication-related traits, including petiole morphology and bolting time. Metabolite profiling uncovers divergence among populations: var. dulce, predominantly consumed raw in Western culinary traditions, exhibits marked reductions in bitter coumarins and alkaloids—a metabolic signature consistent with fresh-eating preferences. Metabolite GWAS map 335,692 loci for 1552 metabolites. We develop genomic prediction models for metabolite abundance to aid breeding. Collectively, our study reveals the genomic and metabolic landscape of celery domestication, and provides hypotheses regarding how cultural practices, alongside regional environmental factors, may have jointly shaped current diversity.